The interchange from southbound Highway 99 to westbound Highway 152 was closed for about two hours Friday morning after a big rig carrying hay overturned, California Highway Patrol reported.
No injuries were reported, said Officer Eric Zuniga, a CHP spokesman.
The incident occurred about 7 a.m. California Department of Transportation closed the interchange to remove hay from the roadway. The interchange was reopened about 9:30 a.m.
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The truck is the third to overturn on Highway 99 this week. A gas tanker carrying 9,000 gallons of fuel overturned in Atwater on a Highway 99 offramp on Tuesday, bursting into flames and killing the driver.
On Wednesday, a big rig carrying liquid cleaning solution struck a guardrail, jackknifed and caught fire. The flames spread to the dry grass near the Highway 152 interchange, just south of Chowchilla. Several roads were closed for hours, but no one was injured.
This story will be updated.